Zanamivir is also considered for use, but it must be inhaled. For example, in the 1918 pandemic: "This horrific disconnect between reassurances and reality destroyed the credibility of those in authority. 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CS1 maint: multiple names: authors list (. Flu viruses can remain infectious for about one week at human body temperature, over 30 days at 0 °C (32 °F), and indefinitely at very low temperatures (such as lakes in northeast Siberia). " "How many mutations would make an avian virus capable of infecting humans efficiently, or how many mutations would render an influenza virus a pandemic strain, is difficult to predict. coordinating efforts among donor and affected nations; increasing transparency in disease reporting and surveillance; and. What happens when a pandemic influenza virus emerges? It is unlikely that seasonal flu vaccines would protect against a pandemic influenza virus.  The rapid spread of this new virus was likely due to a general lack of pre-existing antibody-mediated immunity in the human population. World Health Organization. In one case, a boy with H5N1 experienced diarrhea followed rapidly by a coma without developing respiratory or flu-like symptoms.. Although we are now in the post pandemic period, the H1N1 (2009) virus is still circulating as one of the seasonal flu strains. An influenza pandemic is a global outbreak of a new influenza A virus that is very different from current and recently circulating human seasonal influenza A viruses.  A vaccine formulated for one year may be ineffective in the following year, since the influenza virus changes rapidly over time and different strains become dominant. For example, Canadian health authorities say that they are developing the capacity to produce 32 million doses within four months, enough vaccine to inoculate every person in the country. Given this picture, it will remain important for people to continue to take prudent steps to protect themselves. Most known strains are extinct strains. In the Fiji islands, it killed 14 percent of the entire population in 16 days. Efforts to deal with pandemics can leave a great deal to be desired because of human selfishness, lack of trust, illegal behavior, and ignorance. ", Highly pathogenic H5N1 avian influenza kills 50% of humans that catch it. , The U.S. government, bracing for the possibility that migrating birds could carry a deadly strain of bird flu to North America, plans to test nearly eight times as many wild birds starting in April 2006 as have been tested in the past decade. Human-to-human spread of the virus in two or more countries in one WHO region. The disease spread rapidly through the rest of the spring, and by 3 May, a total of 787 confirmed cases had been reported worldwide. Designation of this phase will indicate that a pandemic is under way.  Several countries, however, have well-developed plans for producing large quantities of vaccine. During a flu pandemic, antiviral drugs would be an important tool to treat and prevent the spread of influenza illness. Pandemics happen when new (novel) influenza A viruses emerge which are able to infect people easily and spread from person to person in an efficient and sustained way. , "[E]fforts by the federal government to prepare for pandemic influenza at the national level include a $100 million DHHS initiative in 2003 to build U.S. vaccine production. It evolved from H2N2 by antigenic shift and caused the Hong Kong Flu pandemic of 1968 and 1969 that killed up to 750,000. In Phase 3, an animal or human-animal influenza reassortant virus has caused sporadic cases or small clusters of disease in people, but has not resulted in human-to-human transmission sufficient to sustain community-level outbreaks. A novel influenza (flu) virus is an influenza A virus that has caused human infection and which is different from current human seasonal influenza A viruses.  (2006) The Bird Flu Pandemic. An influenza pandemic is an epidemic of an influenza virus that spreads across a large region (either multiple continents or worldwide) and infects a large proportion of the population. Both Tamiflu and Relenza are in short supply, and production capabilities are limited in the medium term. Seasonal flu vaccines that are used annually protect against currently circulating human influenza A and B viruses. Are there vaccines to protect against pandemic flu? Such steps include the use of influenza vaccine when available and especially if they are in a group recognised to be at higher risk for severe illness. Spread of a pandemic influenza virus may occur in multiple disease “waves” that are separated by several months. July 2009", "US Food & Drug Administration. We have examined sequences from the 1918 strain, which is the only pandemic influenza virus that could be entirely derived from avian strains.  Controversy arose in October 2005, after the H1N1 genome was published in the journal, Science. The Malaysian government has developed a National Influenza Pandemic Preparedness Plan (NIPPP) which serves as a time bound guide for preparedness and response plan for influenza pandemic. " By the end of the pandemic, there were more than 18,000 laboratory-confirmed deaths from H1N1. The first dose primes the immune system and the second dose creates the protective response.